News

Ascletis has decided not to pursue additional clinical trials on the farnesoid X receptor (FXR) agonist ASC42 for the treatment of PBC.

A study found that cholestatic pruritus is under-documented in patient medical records, compared to patient-reported responses.

The European Medicines Agency has accepted for review the Marketing Authorization Application (MAA) for seladelpar in PBC.

The FDA has accepted the supplemental New Drug Application for Intercept’s Ocaliva for the treatment of PBC.

The drug elafibranor appears to be effective and safe for the treatment of primary biliary cholangitis (PBC) in a phase 3 trial.

Using a two-sample Mendelian randomization (MR) analysis, researchers found a genetic association between PBC and CTDs.

Phase 1 results showed TH104 had a positive safety and efficacy profile, and Tharimmune is on track to begin a phase 2 study this year.

A randomized survival forest model in machine learning was used to construct a prognostic model for cirrhosis in primary biliary cholangitis (PBC).

A study showed a rare case of primary biliary cholangitis (PBC) with features of autoimmune hepatitis in an adolescent with a genetic defect.

Autotaxin may be an effective noninvasive biomarker for the diagnosis and prognosis of primary biliary cholangitis (PBC), researchers stated.